Developing New, Affordable TB Vaccines

Partnership to develop new TB vaccines that are affordable and accessable to all those who need them.


"The most effective way to stop the global TB epidemic is to prevent the spread of M. tuberculosis, but that is becoming increasingly difficult with the rise of multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB), the latter of which is resistant to most first- and second-line drugs.

Aeras was founded in 1997 to develop new concepts and tools to control the global TB epidemic. It is the goal of Aeras to develop, test, characterize, license, manufacture and distribute at least one new TB vaccine within 10 years.

GSK has long been committed to developing an effective tool against TB disease. For about 10 years, the company has been working with organizations such as Aeras in the development of a TB vaccine to ensure access to an effective TB vaccine to the populations who need it most. GSK’s current M72/AS01E candidate prophylactic vaccine has been tested in early stage Phase I/II studies in Europe and TB endemic countries. In October 2012, GSK and Aeras entered into a new agreement with the goal of assessing the potential efficacy of the M72/AS01E candidate vaccine against TB disease and to investigate biomarkers of risk for TB disease and possible correlates of protection, which would benefit the TB vaccine field in general. The trial is targeted to start in summer 2014 and will enrol more than 3500 participants across several trial sites in South Africa, Zambia and Kenya."


  • GlaxoSmithKline (GSK)

    Goods Supplier
    United Kingdom | Staff size: 10,000+

    We are a science-led global healthcare company that researches and develops a broad range of innovative medicines and brands. Our products are used by millions of people around the world,...

  • Johnson & Johnson

    Service Providers, Goods Supplier
    United States | Staff size: 10,000+

    At Johnson & Johnson we are committed to:

    • Building healthy communities through innovative and impactful healthcare solutions and...
  • Sanofi Espoir Foundation

    Advocacy NGO
    United States | Staff size: Unknown

    The Sanofi Espoir Corporate Foundation was created in October 2010 by Sanofi to leverage more than 15 years of commitment to international solidarity.

    It is dedicated to...

  • Bill & Melinda Gates Foundation (B&MGF)

    United States | Staff size: 1001-5000
    Guided by the belief that every life has equal value, the Bill & Melinda Gates Foundation works to help all people lead healthy, productive...
  • TuBerculosis Vaccine Initiative (TBVI)

    Implementing NGO
    Netherlands | Staff size: 6-25

    The TuBerculosis Vaccine Initiative (TBVI) is a non-profit foundation that facilitates the discovery and development of new, safe and effective TB vaccines that are accessible and affordable for...

  • University of Cape Town

    South Africa | Staff size: Unknown

    The University of Cape Town (UCT) is South Africa's oldest university, and is one of Africa's leading teaching and research institutions.

    UCT aspires to become a premier academic meeting...

  • Wellcome Trust

    Foundation, Funding Agencies
    United Kingdom | Staff size: 501-1000

    Wellcome Trust is a global charitable foundation, both politically and financially independent. The foundation supports scientists and researchers, take on big problems, fuel imaginations, and...

  • Department for International Development (DFID) - United Kingdom

    Funding Agencies
    United Kingdom | Staff size: 1001-5000

    The Department for International Development (DFID) leads the UK’s work to end extreme poverty. DFID is tackling the global challenges of time including poverty and disease, mass...

  • Chinese Center for Disease Control and Prevention (China CDC)

    Advocacy NGO
    China | Staff size: Unknown

    Chinese Center for Disease Control and Prevention (China CDC) is a nonprofit institution working in the fields of disease control and prevention, public health management and provision of...

  • Infectious Disease Research Institute (IDRI)

    United States | Staff size: 101-250

    Devastating infectious diseases cause suffering and death for millions of people around the globe. For many years, most of the investment in addressing these global health challenges was focused...

  • National Institutes of Health (NIH) - United States

    Institute, Funding Agencies
    United States | Staff size: 10,000+

    The National Institutes of Health (NIH), a part of the U.S. Department of Health and Human Services, is the nation’s medical research agency—making important medical discoveries that...

  • Organization for Educational Technology and Curriculum (OETC)

    Implementing NGO
    United States | Staff size: 6-25

    The Organization for Educational Technology and Curriculum is a non-profit dedicated to providing schools access to technology. OETC helps schools access technology by lowering the price through...

  • Australian Department of Foreign Affairs and Trade (DFAT)

    Australia | Staff size: Unknown

    The department’s purpose is to help make Australia stronger, safer and more prosperous by promoting and protecting our interests internationally and contributing to global stability and...

  • Rijksoverheid

    Association, Government
    Netherlands | Staff size: 10,000+

    The website is the joint website of the 11 ministries . Ministries are engaged in legislative proposals , rules and policy plans. At...

  • Crucell

    Goods Supplier
    Netherlands | Staff size: 501-1000

    Crucell is a biotechnology company specializing in vaccines and biopharmaceutical technologies. The firm, a subsidiary of Johnson & Johnson, is headquartered in Leiden,...

  • Statens Serum Institut (SSI)

    Denmark | Staff size: 1001-5000

    SSI is a public enterprise under the Danish Ministry of Health. For more than 100 years SSI’s main task has been to secure the preparedness towards infectious diseases and congenital...

  • China National Biotec Group (CNBG)

    Institute, Goods Supplier
    China | Staff size: 10,000+

    China National Biotec Group (CNBG), is a subsidiary of China National Pharmaceutical Group Corporation (SINOPHARM). As the first manufacturer of vaccines and blood products in China and with 6...

  • Global Health Innovative Technology Fund (GHIT Fund)

    Funding Agencies
    Japan | Staff size: 26-50

    The Global Health Innovative Technology Fund (GHIT Fund) is a public-private partnership that leverages Japanese innovation, investment, and leadership to advance the development of new health...

  • European & Developing Countries Clinical Trials Partnership (EDCTP)

    Implementing NGO
    South Africa | Staff size: 26-50

    The European and Developing Countries Clinical Trials Partnership (EDCTP) was created in 2003 as a European response to the global health crisis caused by the three main poverty-related diseases...

  • U.S. Food and Drug Administration (FDA)

    Staff size: 5001-10,000

    The FDA is responsible for protecting the public health by assuring the safety, efficacy, and security of human and veterinary drugs, biological products, medical devices, our nation’s...

  • Aeras

    Implementing NGO
    United States | Staff size: 101-250

    Aeras is a nonprofit biotechnology organization developing new, effective tuberculosis (TB) vaccines that are affordable and accessible to all who need them. We work through partnerships in both...

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Key Information

LocationEastern Europe, West Africa, Central Africa, Central Asia, East Asia and Pacific, Eastern Africa, Latin America and Caribbean, North Africa and Middle East, South Asia, Southern Africa
  • Start Date 2004