Alliance to Protect Lives of Millions through Vaccines

GAVI Alliance was founded in 2000 by some of the world's leading donors and pharmaceutical companies to protect lives and health of millions of people around the world through the widespread use of vaccines.

GAVI Alliance

The GAVI Alliance was founded in 2000 by the Bill & Melinda Gates Foundation, the World Bank, the WHO, UNICEF and vaccine manufacturers, including Sanofi Pasteur, Pfizer, MSD, GSK, Novartis, and Crucell, subsidiary of Johnson & Johnson. Committed to saving children’s lives and protecting people’s health through the widespread use of vaccines, GAVI’s driving objective is to make a critical contribution to global immunization goals by supporting immunization programs and health systems, and accelerating the introduction of new vaccines.

Industry partners invest in the development of new vaccines and in enhanced global vaccine manufacturing capacity, including facilities in developing countries. They also help to educate healthcare providers and develop technologies to facilitate vaccine distribution.

GAVI addresses three critical gaps in the provision of vaccines:

• between children for whom immunization is a given and the 23.2 million children worldwide with no access to vaccines;
• between the introduction of a new vaccine in rich countries and the average 10-15 years required for the same vaccine to reach low-income countries;
• between the need for new vaccines in developing countries and the lack of research and funds to provide them.

GAVI supports new and underused vaccines, health system strengthening, immunization services, injection safety and civil society organizations In total, GAVI has committed USD 7.2 billion since 2000. Eighty (80) percent has been committed towards the purchase of vaccines. The GAVI Fund provides financial support to low-income countries, based upon applications to and recommendations by the GAVI Alliance Board. Besides, industry partners invest in the development of new vaccines and in enhanced global vaccine manufacturing capacity, including facilities in developing countries. They also help to educate healthcare providers and develop technologies to facilitate vaccine distribution.

Between 2000 and 2008, programs within the GAVI Alliance made it possible to immunize 213 million children, which represent at least 3.4 million lives saved. By the end of 2013, GAVI had supported the immunization of 400 million additional children, who might not otherwise have had access to vaccines, and prevented over 6 million future deaths.

GAVI-supported vaccine campaigns have resulted in a further 100 million individuals being immunised against meningitis A and 68 million against yellow fever since 2000. The offensive also targets the world’s two biggest child killers, pneumonia and diarrhea. GAVI has the potential to immunize 250 million children by 2015 and prevent another four million future deaths.

Partners

• GlaxoSmithKline (GSK)

  Goods Supplier
  United Kingdom | Staff size: 10,000+

  We are a science-led global healthcare company that researches and develops a broad range of innovative medicines and brands. Our products are used by millions of people around the world,...

  We are a science-led global healthcare company that researches and develops a broad range of innovative medicines and brands. Our products are used by millions of people around the world, helping them to do more, feel better and live longer.

  We have three primary areas of business in pharmaceuticals, vaccines and consumer healthcare. Our commercial success depends on creating innovative new products and making these accessible to as many people who need them as possible. By achieving this, we will be able to grow our business and provide benefits to patients, consumers, society, our employees and our shareholders.

  With our headquarters in the UK, we have a wide geographical reach. We have offices in more than 115 countries, major research centres in the UK, USA, Spain, Belgium and China and an extensive manufacturing network with around 70 sites globally.

  Research is vitally important to the success of our business, and we spent just under £4 billion in 2011 in our search to develop new medicines, vaccines and innovating consumer products. We are one of the few healthcare companies researching medicines and vaccines for the World Health Organisation’s three priority diseases - HIV/AIDS, tuberculosis and malaria.

  Pharmaceuticals

  Our pharmaceuticals business researches, develops and makes available medicines that treat a variety of serious and chronic diseases. We have medicines available or in development in a wide range of areas including:

  • infectious diseases
  • cancer
  • epilepsy
  • heart disease
  • asthma and chronic obstructive pulmonary disease

  HIV/AIDS

  VaccinesOur vaccine business is one of the largest in the world, with over 1.1 billion doses distributed to 173 countries. We produce paediatric and adult vaccines to prevent a range of infectious diseases including:

  • hepatitis A and B
  • diphtheria, tetanus and whooping cough
  • measles, mumps and rubella
  • polio
  • typhoid
  • influenza
  • bacterial meningitis

  Consumer Healthcare

  Through our consumer healthcare business, we market a range of consumer health products based on scientific innovation. We have leading positions in four main categories:

  • oral health
  • nutritionals
  • wellness
  • skin health

• Johnson & Johnson

  Service Providers, Goods Supplier
  United States | Staff size: 10,000+

  Caring for the world, one person at a time... inspires and unites the people of Johnson & Johnson. They embrace research and science - bringing innovative ideas, products and services to...

  Caring for the world, one person at a time... inspires and unites the people of Johnson & Johnson. They embrace research and science - bringing innovative ideas, products and services to advance the health and well-being of people.

  Employees of the Johnson & Johnson Family of Companies work with partners in health care to touch the lives of over a billion people every day, throughout the world.

  Their Family of Companies comprises:

  -The world’s premier consumer health company.
  -The world’s largest and most diverse medical devices company.
  -The world’s third-largest biologics company.
  -And the world’s sixth-largest pharmaceuticals company.

  They have more than 250 operating companies in 57 countries employing 120,200 people. Their worldwide headquarters is in New Brunswick, New Jersey, USA.

  At Johnson & Johnson they are committed to:

  -Building healthy communities through innovative and impactful healthcare solutions and partnerships.
  -Uniting Janssen’s scientific capabilities and innovative access models to address unmet health needs across the world within a dedicated Global Public Health group.
  -Prioritizing maternal and newborn survival and health, infectious and neglected tropical diseases, and strengthening healthcare systems across the Johnson and Johnson family of companies.

• Merck

  Service Providers, Goods Supplier
  United States | Staff size: 10,000+

  Merck is an innovative, global healthcare leader that is committed to improving health and well-being around the world. At Merck, they're applying their global reach, financial strength and...

  Merck is an innovative, global healthcare leader that is committed to improving health and well-being around the world. At Merck, they're applying their global reach, financial strength and scientific excellence to do more of what they're passionate about: improving health and improving lives.

  Their product offering categories include heart and respiratory health, infectious diseases, sun care and women's health. They continue to focus their research on conditions that affect millions of people around the world - diseases like Alzheimer's, diabetes and cancer - while expanding our strengths in areas like vaccines and biologics.

  They also devote extensive time and energy to increasing access to medicines and vaccines through far-reaching programs that donate and deliver their products to the people who need them.

  At Merck, corporate responsibility is their daily commitment to tackle the world's biggest health challenges by discovering better ways to make a difference in everything they do. It is a simple promise that is embedded in their business and informs all their individual actions.

  VISION

  To make a difference in the lives of people globally through our innovative medicines, vaccines, and animal health products. They are committed to being the premier, research-intensive biopharmaceutical company and are dedicated to providing leading innovations and solutions for today and the future.

  MISSION

  To discover, develop and provide innovative products and services that save and improve lives around the world.

  Access to Health

  It is unacceptable that the vast majority of people around the world are unable to benefit from advances in medicines and healthcare. To help address this global dilemma, we are committed to discovering smart, sustainable ways to expand access to healthcare. Their new Statement of Guiding Principles, which guide their worldwide approach to access to health, outline specific c goals to assure progress across their business from R&D and the supply chain to commercialization and investment in local infrastructure.

  Environmental Sustainability

  They’re making sure they respect the earth’s resources with a commitment to discover environmentally sustainable ways to meet the world’s health needs. They have defined a road map to guide their progress, from reducing their environmental footprint in the short term, to transforming their entire value chain over the longer term.

  Ethics and Transparency

  They are transparent and open not just because we believe it’s right, but because it’s central to how they serve the people who depend on them. They’re committed to ethical behavior and transparent communications across their global business. And they’re working every day to earn their stakeholders’ trust by engaging audiences on all sides of the issues that matter, and by going beyond mandatory disclosure to proactively communicate key information in greater detail than ever before.

  Employees

  The talent, diversity and integrity of Merck’s people drive their success. They’re committed to discovering new ways to help their employees and their business thrive. This means supporting employees not just as workers, but as people — developing resources and opportunities that help employees grow professionally, helping to improve the health of their employees and their families, and encouraging them to get involved in their communities in ways that are meaningful.

• Novartis AG

  Goods Supplier
  Switzerland | Staff size: 10,000+

  Novartis AG, was incorporated on 1996, provides healthcare solutions. The Company is a multinational group of companies specializing in the research, development, manufacturing and marketing of...

  Novartis AG, was incorporated on 1996, provides healthcare solutions. The Company is a multinational group of companies specializing in the research, development, manufacturing and marketing of a range of healthcare products led by pharmaceuticals. Its portfolio includes medicines, eye care, cost-saving generic pharmaceuticals, preventive vaccines and diagnostic tools, over-the-counter and animal health products. The Company has five segments:

  • Pharmaceuticals: innovative patent-protected medicines
  • Alcon: global leader in eye care with surgical, ophthalmology and consumer products
  • Sandoz: affordable, high-quality generic medicines and biosimilars
  • Consumer Health: self-medication products and treatments for animals
  • Vaccines and Diagnostics: vaccines and diagnostic tools to protect against life-threatening diseases

  Corporate Social Responsibility

  Our commitment: improving health

  We aim to improve global health. Through our business, we make an important contribution to society: We discover and develop innovative healthcare products, targeting unmet medical needs. Novartis is the only healthcare company with leading positions in pharmaceuticals, eye care, generic medicines, vaccines, as well as consumer products.

  Access to healthcare

  Novartis collaborates with others to help address some of the world’s greatest health challenges. To help do that, Novartis’ corporate responsibility programs help more people secure the healthcare they need, regardless of where they live. Novartis has done this for a long time, largely through philanthropic and not-for-profit programs.

  Novartis has concentrated its efforts in controlling malaria, leprosy, tuberculosis, noncommunicable diseases and pioneering new business approaches to reach underserved patients, and finding new treatments and adaptive solutions to improve health for people around the world. In 2013, these efforts reached more than 100 million patients.

  Responsible business practices

  Novartis is committed to being a leader in corporate responsibility, and were one of the first signatories to the United Nations Global Compact, the world's largest corporate citizenship initiative. The Global Compact calls on business and other stakeholders to support key principles in the areas of human rights, labor, environment and anti-corruption. These standards are embedded throughout our operations, and we strive for continuous improvement by measuring, monitoring and reporting on our progress.

• Pfizer

  Institute, Goods Supplier
  United States | Staff size: 1001-5000

  At Pfizer, they apply science and their global resources to bring therapies to people that extend and significantly improve their lives.

  They strive to set the standard for quality,...

  At Pfizer, they apply science and their global resources to bring therapies to people that extend and significantly improve their lives.

  They strive to set the standard for quality, safety and value in the discovery, development and manufacture of health care products. Their global portfolio includes medicines and vaccines as well as many of the world's best-known consumer health care products.

  Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of their time. Consistent with their responsibility as one of the world's premier innovative biopharmaceutical companies, they collaborate with health care providers, governments and local communities to support and expand access to reliable, affordable health care around the world. For more than 150 years, Pfizer has worked to make a difference for all who rely on them.

• Sanofi Espoir Foundation

  Advocacy NGO
  United States | Staff size: Unknown

  The Sanofi Espoir Corporate Foundation was created in October 2010 by Sanofi to leverage more than 15 years of commitment to international solidarity.

  It is dedicated to...

  The Sanofi Espoir Corporate Foundation was created in October 2010 by Sanofi to leverage more than 15 years of commitment to international solidarity.

  It is dedicated to helping reduce healthcare inequalities, particularly among the world’s most needy communities, as part of its social responsibility agenda.

  Its actions revolve around three major objectives: controlling childhood cancer, fighting against maternal and child mortality, and ensuring access to healthcare for the world’s poorest populations.

  The Foundation provides support to field personnel with the aim of strengthening local expertise in addressing every link in the healthcare chain.

  In addition to responding to humanitarian emergencies, the Foundation’s actions are in line with the Millennium Development Goals, particularly those relating to fighting diseases, improving maternal and neonatal health, promoting gender equality and empowering women, fighting poverty and implementing a global partnership for development.

  The Foundation provides a dedicated operating framework, a governance and additional resources to gain better leverage from initiatives already underway, and a stimulus for new projects as an ideas lab.

• Bill & Melinda Gates Foundation (B&MGF)

  Foundation
  United States | Staff size: 1001-5000
  Guided by the belief that every life has equal value, the Bill & Melinda Gates Foundation works to help all people lead healthy, productive...

  Guided by the belief that every life has equal value, the Bill & Melinda Gates Foundation works to help all people lead healthy, productive lives. In developing countries, it focuses on improving people's health and giving them the chance to lift themselves out of hunger and extreme poverty. In the United States, it seeks to ensure that all people—especially those with the fewest resources—have access to the opportunities they need to succeed in school and life. Based in Seattle, Washington, the foundation is led by CEO Dr. Susan Desmond-Hellmann and Co-chair William H. Gates Sr., under the direction of Bill and Melinda Gates and Warren Buffett. They work with governments and private partners to foster greater public awareness of urgent global issues. Every year, millions of people find ways to transition out of poverty—by adopting new farming technologies, investing in new business opportunities, or finding new jobs. B&MGF believes women and girls have a unique power to reshape societies. One of their focuses is also on global health goals: they provide effective vaccines, drugs, and diagnostics and to develop innovative approaches to deliver health services to those who need it most.

• Crucell

  Goods Supplier
  Netherlands | Staff size: 501-1000

  Crucell is a biotechnology company specializing in vaccines and biopharmaceutical technologies. The firm, a subsidiary of Johnson & Johnson, is headquartered in Leiden,...

  Crucell is a biotechnology company specializing in vaccines and biopharmaceutical technologies. The firm, a subsidiary of Johnson & Johnson, is headquartered in Leiden, Netherlands.

  Crucell joined the Janssen Pharmaceutical Companies of Johnson & Johnson in February 2011 and as of October 2014 Crucell is changing its identity into Janssen. For Janssen, the acquisition of Crucell has provided a firm foothold in the increasingly important field of disease prevention.

  Currently they are combating twelve major infectious diseases with their range of marketed vaccines in the paediatric, travel and endemic and respiratory fields.

  Innovation is the drive force behind their strong research & development (R&D) pipeline, with promising products in pre-clinical and clinical development. Crucell product candidates include flu-mAb, and antibody product effective against a broad range of influenza virus strains, tuberculosis and malaria vaccines, as well as a rabies monoclonal antibody combination-all produced on our unique PER.C6® human-cell technology.

  Headquartered in Leiden, the Netherlands, Crucell currently employs 1400 people and has offices in China, Indonesia, Italy, Korea, Malaysia, Spain, Sweden, Switzerland, the UK the USA and Vietnam.

• Global Alliance for Vaccines and Immunisation (GAVI)

  Funding Agencies, Implementing NGO
  United States | Staff size: 101-250

  Gavi is an international organisation that was created in 2000 to improve access to new and underused vaccines for children living in the world’s poorest countries. Based in Geneva,...

  Gavi is an international organisation that was created in 2000 to improve access to new and underused vaccines for children living in the world’s poorest countries. Based in Geneva, Switzerland, Gavi is the Vaccine Alliance, which brings together public and private sectors with the shared goal of creating equal access to vaccines for children, wherever they live.

  A new approach to a global problem

  The Gavi story begins towards the end of the 20th century, when global immunisation efforts were beginning to plateau. Despite the promising progress of the previous two decades, by the Expanded Programme on Immunization (EPI), there were still 30 million children living in poor countries who were not fully immunised. Coverage was stagnating and in some places even declining. And even though new life-saving vaccines were becoming available, beyond the original six EPI vaccines, virtually none were reaching children in developing countries, those who needed them most, because they were too expensive.

  What was needed was an entirely new approach. So, with help of a US$ 750 million five-year pledge from the Bill & Melinda Gates Foundation, in January 2000 the Global Alliance for Vaccines and Immunisation (Gavi) was created. A unique public-private partnership, Gavi was created to bring together the best of what key UN agencies, governments, the vaccine industry, private sector and civil society had to offer in order to improve childhood immunisation coverage in poor countries and to accelerate access to new vaccines.

  This model was designed to leverage not just financial resources but expertise too, to help make vaccines more affordable, more available and their provision more sustainable, by working towards a point where developing countries can pay for them themselves. It was a 21st century development model for a new millennium and one which works, by 2015 reaching 500 million additional children since its creation and preventing more than 7 million deaths in the process. And that’s just the beginning. Looking ahead Gavi’s vision is to ramp up this number, reaching an additional 300 million children between 2016 and 2020, preventing a further 5-6 million more deaths.

  Created in 2000, Gavi is an international organisation - a global Vaccine Alliance, bringing together public and private sectors with the shared goal of creating equal access to new and underused vaccines for children living in the world’s poorest countries.

• United Nations Children's Fund (UNICEF)

  Funding Agencies
  United States | Staff size: 10,000+

  UNICEF works in 190 countries and territories to protect the rights of every child. UNICEF has spent 70 years working to improve the lives of children and their families. Defending children's...

  UNICEF works in 190 countries and territories to protect the rights of every child. UNICEF has spent 70 years working to improve the lives of children and their families. Defending children's rights throughout their lives requires a global presence, aiming to produce results and understand their effects.

  They believe that nurturing and caring for children are the cornerstones of human progress. UNICEF was created with this purpose in mind – to work with others to overcome the obstacles that poverty, violence, disease and discrimination place in a child’s path.
  
  What They Do

  Child safety through protection and inclusion

  UNICEF works to improve the policies and services that protect all children. They aim to make the world a safe and inclusive place for children to grow.

  Helping children to survive and thrive

  Child mortality has decreased globally. UNICEF works to make sure solutions reach all children, everywhere.

  Education is the key to opportunities

  UNICEF believes that quality education is a right for all children, whether in the developing world or amidst conflict and crisis.

  Responding to emergencies

  Wherever there is a crisis, UNICEF strives to reach children and families in the hardest hit regions with lifesaving resources.

  Creating change for women and girls

  UNICEF fights for the equal rights of women and girls, with their full participation in political, social and economic development around the world.

  Creating the world that children deserve

  UNICEF believes that the complex challenges children face can be met with innovative, creative solutions backed by rigorous research.

  Supplying solutions in the field

  UNICEF works to provide and transport critical medicine, aid and supplies to the world’s most needy children.

  Data and field work driving action

  UNICEF’s global programmes and initiatives are grounded in rigorous research and thoughtful analysis. S

• World Bank Group

  Funding Agencies
  United States | Staff size: 10,000+

  The World Bank is a vital source of financial and technical assistance to developing countries around the world. Their mission is to fight poverty with passion and professionalism for lasting...

  The World Bank is a vital source of financial and technical assistance to developing countries around the world. Their mission is to fight poverty with passion and professionalism for lasting results and to help people help themselves and their environment by providing resources, sharing knowledge, building capacity and forging partnerships in the public and private sectors.

  
  Established in 1944, the World Bank Group is headquartered in Washington, D.C. They have more than 10,000 employees in more than 120 offices worldwide.

  
  The World Bank Group consists of five organizations:

  
  The International Bank for Reconstruction and Development

  
  The International Bank for Reconstruction and Development (IBRD) lends to governments of middle-income and creditworthy low-income countries.

  
  The International Development Association

  
  The International Development Association (IDA) provides interest-free loans — called credits — and grants to governments of the poorest countries.

  
  Together, IBRD and IDA make up the World Bank.

  
  The International Finance Corporation

  
  The International Finance Corporation (IFC) is the largest global development institution focused exclusively on the private sector. We help developing countries achieve sustainable growth by financing investment, mobilizing capital in international financial markets, and providing advisory services to businesses and governments.

  
  The Multilateral Investment Guarantee Agency

  
  The Multilateral Investment Guarantee Agency (MIGA) was created in 1988 to promote foreign direct investment into developing countries to support economic growth, reduce poverty, and improve people’s lives. MIGA fulfills this mandate by offering political risk insurance (guarantees) to investors and lenders.

  
  The International Centre for Settlement of Investment Disputes

  
  The International Centre for Settlement of Investment Disputes (ICSID) provides international facilities for conciliation and arbitration of investment disputes.

  Products and Services

  
  The World Bank Group offers a wide range of solutions to meet development challenges, all designed to support governments in reducing poverty and boosting prosperity:

  
  Financing Instruments
  

  • Investment Project Financing provides IBRD loan, IDA credit/grant and guarantee financing to governments for activities that create the physical/social infrastructure necessary to reduce poverty and create sustainable development.
    
  • Development Policy Financing provides IBRD loan, IDA credit/grant and guarantee budget support to governments or a political subdivision for a program of policy and institutional actions to help achieve sustainable, shared growth and poverty reduction.
    
  • Program-for-Results links disbursement of funds directly to the delivery of defined results, helping countries improve the design and implementation of their own development programs and achieve lasting results by strengthening institutions and building capacity.
    
  • Trust funds and grants allow scaling up of activities, notably in fragile and crisis-affected situations; enable the Bank Group to provide support when our ability to lend is limited; provide immediate assistance in response to natural disasters and other emergencies; and pilot innovations that are later mainstreamed into our operations.
    
  • Private sector options for financing, direct investment and guarantees are provided by MIGA and IFC.
    
  • Customized options and risk management
    

  
  Services

  • Technical Assistance (TA)
  • Reimbursable Advisory Services (RAS)
  • Economic and Sector Work (ESW)
  • Business advice
  • Donor aid coordination

• World Health Organization (WHO)

  Funding Agencies
  Staff size: 5001-10,000

  WHO (World Health Organisation) is the directing and coordinating authority for health within the United Nations system. It is responsible for providing leadership on global health matters,...

  WHO (World Health Organisation) is the directing and coordinating authority for health within the United Nations system. It is responsible for providing leadership on global health matters, shaping the health research agenda, setting norms and standards, articulating evidence-based policy options, providing technical support to countries and monitoring and assessing health trends. WHO was founded in 1948.

  193 countries and two associate members are WHO’s membership. They meet every year at the World Health Assembly in Geneva to set policy for the Organization, approve the Organization’s budget.

  Over 8000 public health experts including doctors, epidemiologists, scientists, managers, administrators and other professionals from all over the world work for WHO in 147 country offices, six regional offices and at the headquarters in Geneva, Switzerland.

  The WHO agenda

  WHO operates in an increasingly complex and rapidly changing landscape. The boundaries of public health action have become blurred, extending into other sectors that influence health opportunities and outcomes. WHO responds to these challenges using a six-point agenda. The six points address two health objectives, two strategic needs, and two operational approaches. The overall performance of WHO will be measured by the impact of its work on women's health and health in Africa.

  1. Promoting development

  2. Fostering health security

  3. Strengthening health systems

  4. Harnessing research, information and evidence

  5. Enhancing partnerships

  6. Improving performance

  The role of WHO in public health

  WHO fulfils its objectives through its core functions:

  • providing leadership on matters critical to health and engaging in partnerships where joint action is needed;
  • shaping the research agenda and stimulating the generation, translation and dissemination of valuable knowledge;
  • setting norms and standards and promoting and monitoring their implementation;
  • articulating ethical and evidence-based policy options;
  • providing technical support, catalysing change, and building sustainable institutional capacity; and
  • monitoring the health situation and assessing health trends

More Resources

• http://partnerships.ifpma.org/partnership/gavi-alliance