Genomic Profiling of Lupus

This partnership between Merck and Pfizer with Broad Institute aims to identify biomarkers relevant to future therapies in the area of Systemic Lupus Erythematosus and Lupus Nephritis.

Genomic Profiling of Lupus

This collaboration of EMD Serono, subsidiary of Merck, and Pfizer, is focused on the genomic profiling of Systemic Lupus Erythematosus (SLE) and Lupus Nephritis (LN) patients.

As part of the collaboration, the Broad Institute will investigate clinical samples obtained from SLE and LN patients, applying biochemical and next-generation sequencing technologies. They will also analyze immune cell subpopulations. The goal is to identify biomarkers to better define target patient populations for future therapies. In addition, through computational modeling approaches, the project aims to identify key molecular drivers of SLE and LN kidney flares, and thereby to discover potential novel drug targets as the basis for innovative therapies.

Under the terms of the agreement, EMD Serono and Pfizer, as sponsoring members, will receive real-time access to all data and analysis. In addition, both companies will have the ability to send a research scientist to the Broad Institute to foster exchange of technology expertise in the area of computational and experimental genomic profiling.

Partners

  • Broad Institute

    Institute
    United States | Staff size: 51-100

    The Eli and Edythe L. Broad Institute of MIT and Harvard, referred to as the Broad Institute, is a biomedical and genomic research center located in Cambridge, Massachusetts, United States. The...

  • Merck

    Goods Supplier, Service Providers
    United States | Staff size: 10,000+

    Merck is an innovative, global healthcare leader that is committed to improving health and well-being around the world. At Merck, they're applying their global reach, financial strength and...

  • Pfizer

    Goods Supplier, Institute
    United States | Staff size: 1001-5000

    At Pfizer, they apply science and their global resources to bring therapies to people that extend and significantly improve their lives.

    They strive to set the standard for quality,...

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Key Information

LocationNorth America, United States
StatusActive
  • Start Date 2014
Sectors