This collaboration of EMD Serono, subsidiary of Merck, and Pfizer, is focused on the genomic profiling of Systemic Lupus Erythematosus (SLE) and Lupus Nephritis (LN) patients.
As part of the collaboration, the Broad Institute will investigate clinical samples obtained from SLE and LN patients, applying biochemical and next-generation sequencing technologies. They will also analyze immune cell subpopulations. The goal is to identify biomarkers to better define target patient populations for future therapies. In addition, through computational modeling approaches, the project aims to identify key molecular drivers of SLE and LN kidney flares, and thereby to discover potential novel drug targets as the basis for innovative therapies.
Under the terms of the agreement, EMD Serono and Pfizer, as sponsoring members, will receive real-time access to all data and analysis. In addition, both companies will have the ability to send a research scientist to the Broad Institute to foster exchange of technology expertise in the area of computational and experimental genomic profiling.
|Location||North America, United States|