Research and Development for Malaria

A global health partnership to discover and develop new malaria compounds that target the liver and blood stage infections and to counter the first signs of resistance to ACTs.

Novartis R&D for Malaria

The Novartis Institute for Tropical Diseases (NITD) is collaborating with the Genomics Institute of the Novartis Research Foundation, Swiss Tropical and Public Health Institute, and Scripps Research Institute to discover and develop new antimalarial compounds that target both Plasmodium falciparum and Plasmodium vivax.

The NITD and its partners are developing a potential one-dose cure for Plasmodium falciparum, and a curative modality for Plasmodium vivax. Two compounds resulting from these drug discovery efforts are currently in Phase II clinical trials, KAE609 and KAF156.

In November 2013, Novartis and collaborators announced the discovery of yet another new malaria drug target and a new compound class with potential to prevent, block and treat malaria. Called imidazopyrazines, this is the third new class of malaria compounds discovered by Novartis scientists within the last five years.


  • Novartis AG

    Goods Supplier
    Switzerland | Staff size: 10,000+

    Novartis AG, was incorporated on 1996, provides healthcare solutions. The Company is a multinational group of companies specializing in the research, development, manufacturing and marketing of...

  • Wellcome Trust

    Funding Agencies, Foundation
    United Kingdom | Staff size: 501-1000

    Wellcome Trust is a global charitable foundation, both politically and financially independent. The foundation supports scientists and researchers, take on big problems, fuel imaginations, and...

  • Swiss Tropical and Public Health Institute (Swiss TPH)

    Institute, Development Consulting
    Switzerland | Staff size: 501-1000

    The Swiss Tropical and Public Health Institute (Swiss TPH) is a world-leading institution in health research, training and services. It improves, maintains and promotes the health of individuals...

  • Singapore Immunology Network

    Singapore | Staff size: 101-250

    The Singapore Immunology Network (SIgN) was launched by the Agency for Science, Technology and Research (A*STAR) with the aim of expanding and strengthening immunology research in Singapore. In...

  • Medicines for Malaria Venture (MMV)

    Foundation, Institute
    United States | Staff size: Unknown

    MMV, a not-for-profit public-private partnership, was established as a foundation in Switzerland. It was created to discover, develop and deliver new, effective and affordable drugs for malaria...

  • Biomedical Primate Research Centre

    Netherlands | Staff size: 101-250

    The Biomedical Primate Research Centre (BPRC) is Europe's largest primate research centre. It is a scientific research institute that performs research that contributes to the identification and...

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Key Information

LocationEast Asia and Pacific, Thailand, United States
  • Start Date 2006
  • End Date 2014
  • ValueUSD 20 Million