Collaboration on Neglected Tropical Diseases

Collaborate for the research of new treatments for nine neglected tropical diseases: Leishmaniasis, Chagas Disease, Human African Trypanosomiasis, Lymphatic Filariasis, Onchocerciasis, Soil-Transmitted Helminthiasis, Dracunculiasis, Fascioliasis and Schistosomiasis.

Sanofi and DNDi Collaboration on Neglected Tropical Diseases

In 2011, Sanofi and DNDi launched a partnership for the research of new treatments for nine neglected tropical diseases (NTDs), listed by the World Health Organization (WHO) for which new, adapted, and efficient tools are urgently needed to treat patients in endemic countries: kinetoplastid diseases (leishmaniasis, Chagas disease, and human African trypanosomiasis), helminth infections (lymphatic filariasis, onchocerciasis, and soil-transmitted helminthiasis), and dracunculiasis, fascioliasis, and schistosomiasis.

In the framework of this agreement, Sanofi brings molecules from its libraries into the partnership, while DNDi and Sanofi collaborate in research activities on innovative molecular scaffolds. The core of the agreement lies in the innovative management of intellectual property generated through the collaboration. The rights to results produced by this partnership will be co-owned by Sanofi and DNDi. The partners will facilitate publication of the results to ensure access to the wider community of researchers focusing on NTDs. The public sector will benefit from the drugs developed through this agreement under the best possible conditions to ease access for patients in all endemic countries, irrespective of their level of economic development.

Since April 2009, Sanofi and DNDi have been working together to develop Fexinidazole, a new and promising drug for the treatment of human African trypanosomiasis (HAT), also known as sleeping sickness. Current therapeutic options are either poorly tolerated or difficult to administer, notably for advanced-stage HAT disease. The development of a new, orally-administered treatment that matches the efficacy of current treatments and improves tolerance will be a major progress.

Partners

  • Sanofi

    Goods Supplier
    Canada | Staff size: Unknown

    Sanofi S.A. is a French multinational pharmaceutical company headquartered in Paris, France, the world's fourth-largest by prescription sales. Sanofi engages in the research and development,...

  • Drugs for Neglected Diseases Initiative (DNDi)

    Association
    United States | Staff size: 251-500

    Drugs for Neglected Diseases initiative (DNDi) is a collaborative, patients’ needs-driven, non-profit drug research and development (R&D) organization that is...

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Key Information

LocationWorldwide
StatusActive
  • Start Date 2011
  • End Date 2016
  • ValueUSD 75 Million
    Sectors