Semi-Synthetic Artemisinin Project

Create a complementary source of non-seasonal, high-quality and affordable artemisinin to supplement the current botanical supply, thereby enabling millions of people infected with malaria to gain consistent access to lower-cost, life-saving artemisinin-based combination therapies (ACTs).

Semi-Synthetic Artemisinin Project

The partnership aims at developing a complementary, semisynthetic, source of artemisinin, to improve the availability of high-quality artemisinin derivatives to drug manufacturers and contribute to stabilizing the price of artemisinin-containing antimalarials to benefit patients and payers. The original idea and the proof of concept were developed at the University of California-Berkeley, the project was then managed by the Institute for One World Health (IOWH), a nonprofit pharmaceutical company. From the proof of concept, a first chemical route was developed on a laboratory scale by Amyris Biotechnologies, a US based Biotech start-up. Sanofi was selected as the manufacturing partner, due to the malaria program within its Access to Medicines department, and because of its production and technological competences and capacity. The Bill & Melinda Gates Foundation (BMGF) provided significant financial support to this project, from its inception to its latest stages.


  • Sanofi

    Goods Supplier
    Canada | Staff size: Unknown

    Sanofi S.A. is a French multinational pharmaceutical company headquartered in Paris, France, the world's fourth-largest by prescription sales. Sanofi engages in the research and development,...

  • Amyris

    Goods Supplier
    United States | Staff size: 251-500

    Amyris delivers high-performance alternatives to petroleum-based products across a wide range of consumer and industry segments. Their products offer customers a way to reduce environmental...

  • Bill & Melinda Gates Foundation (B&MGF)

    United States | Staff size: 1001-5000
    Guided by the belief that every life has equal value, the Bill & Melinda Gates Foundation works to help all people lead healthy, productive...
  • PATH

    Implementing NGO
    United States | Staff size: 501-1000

    They dare to believe that innovation can change the world

    PATH is the leader in global health innovation. An international nonprofit organization, they save lives and improve health,...

  • University of California, Berkeley

    Staff size: 10,000+

    Founded in 1868 as the flagship campus of the University of California, UC Berkeley is a public institution with a long history of academic excellence, groundbreaking research, and social and...

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Key Information

LocationEast Asia and Pacific, Zimbabwe, Zambia, Viet Nam, Uganda, Togo, Thailand, Tanzania, Swaziland, Sudan, Southern Sudan, South Africa, Somalia, Sierra Leone, Seychelles, Senegal, Sao Tome and Principe, Rwanda, Nigeria, Niger, Namibia, Myanmar, Mozambique, Mauritius, Mauritania, Mali, Malaysia, Malawi, Madagascar, Liberia, Lesotho, Laos, Kenya, Indonesia, India, Guinea-Bissau, Guinea, Ghana, Gambia, Gabon, Ethiopia, Eritrea, Equatorial Guinea, Cote d Ivoire, Congo, The Republic of, Congo, The Democratic Republic of, Comoros, Chad, Central African Republic, Cape Verde, Cameroon, Cambodia, Burundi, Burkina Faso, Botswana, Benin, Bangladesh, Angola, West Africa, Southern Africa, South Asia, Eastern Africa, Central Africa
  • Start Date 2004