Multidrug-resistant tuberculosis is a crisis. The World Health Organization reports that by best estimates, 480,000 people contracted multidrug-resistant TB in 2014. Without treatment, MDR-TB is a debilitating, lethal disease. It spreads through the air, meaning that a single instance of MDR-TB can put many people at risk of infection. And yet three-quarters of people with MDR-TB never even receive a diagnosis. Of the few people with MDR-TB who begin treatment, only half are treated successfully.
MDR-TB exists in virtually all countries. What’s more, since it was first described in the medical literature just a decade ago, at least 100 countries have reported cases of extensively drug-resistant TB — an advanced form resistant to medicines reserved solely for treating drug-resistant strains. In the past few years, countries have begun reporting cases of people sick with TB that is resistant to all available medicines.
MDR-TB is one of the most complex illnesses to treat, and one of the most difficult treatments to endure.