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    • Opinion
    • World Tuberculosis Day

    5 ways to bring about a TB resistance 'paradigm shift'

    How can the global health community bring about the "paradigm shift" needed to confront tuberculosis resistance? TB programs must do a much better job treating the disease and providing the quality care that prevents it from becoming drug-resistant in the first place, writes José Luis Castro, executive director of the International Union Against Tuberculosis and Lung Disease, in this guest commentary.

    By José Luis Castro // 24 March 2016

    Multidrug-resistant tuberculosis is a crisis. The World Health Organization reports that by best estimates, 480,000 people contracted multidrug-resistant TB in 2014. Without treatment, MDR-TB is a debilitating, lethal disease. It spreads through the air, meaning that a single instance of MDR-TB can put many people at risk of infection. And yet three-quarters of people with MDR-TB never even receive a diagnosis. Of the few people with MDR-TB who begin treatment, only half are treated successfully.

    MDR-TB exists in virtually all countries. What’s more, since it was first described in the medical literature just a decade ago, at least 100 countries have reported cases of extensively drug-resistant TB — an advanced form resistant to medicines reserved solely for treating drug-resistant strains. In the past few years, countries have begun reporting cases of people sick with TB that is resistant to all available medicines.

    MDR-TB is one of the most complex illnesses to treat, and one of the most difficult treatments to endure.

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    Printing articles to share with others is a breach of our terms and conditions and copyright policy. Please use the sharing options on the left side of the article. Devex Pro members may share up to 10 articles per month using the Pro share tool ( ).
    The views in this opinion piece do not necessarily reflect Devex's editorial views.

    About the author

    • José Luis Castro

      José Luis Castro

      José Luis Castro is president and CEO at Vital Strategies, where he has led a rapid expansion of its portfolio and worked with governments to tackle the world’s leading killers, primarily in low- and middle-income countries. The organization now reaches into 73 countries and has touched the lives of more than 2 billion people.

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