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    South Africa's lax patent laws threaten mRNA hub sustainability

    Moderna holds far-reaching patents on mRNA technology in South Africa that could block future mRNA innovations from ever coming to market in the country that helped birth them.

    By Laura López González // 09 March 2023

    South Africa’s lax patent laws could block its future access to messenger RNA vaccines and treatments. They could also lock the World Health Organization’s mRNA hub — located in Cape Town — out of sub-Saharan Africa’s biggest pharmaceutical market right on its doorstep.

    In June 2021, WHO announced the creation of its first mRNA hub at pharmaceutical company Afrigen Biologics and Vaccines’ Cape Town laboratories. The hub is a response to the vaccine inequity that marked the early phases of the COVID-19 pandemic.

    If WHO could support South African scientists to develop a home-grown mRNA vaccine, they could teach the technology to a network of other  emerging producers — known as “spokes.” The end result? A new class of emerging vaccine manufacturers in low- and middle-income countries. Together, this new cadre would not only increase the availability of affordable COVID-19 vaccines but also of future immunizations, finally breaking a cycle of vaccine hoarding during pandemics. 

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    More reading:

    ► South Africa's mRNA hub confronts old problems and new directions

    ► US forges partnership with South Africa's mRNA tech transfer hub

    ► Without shared tech, South Africa's mRNA COVID-19 jab faces 2-year lag

    • Global Health
    • Innovation & ICT
    • Private Sector
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    • Democracy, Human Rights & Governance
    • ModernaTX, Inc.
    • Afrigen
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    About the author

    • Laura López González

      Laura López González@LLopezGonzalez

      Laura López González is a freelance health journalist and editor with 15 years of experience covering health in the global south from Johannesburg, South Africa. Her work has appeared in outlets such as Al Jazeera, the Guardian, and El Pais.

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