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    Opinion: Bridging the vaccine gap threatening Africa

    Developing, producing, and supplying a vaccine for the world is an extraordinarily complicated challenge. AstraZeneca’s Barbara Nel weighs in on the lessons learned so far, and the challenges still to come.

    By Barbara Nel // 28 July 2021
    A vaccine storage warehouse at the Kinkole commune in Kinshasa, Democratic Republic of Congo. Photo by: Ray / UNICEF

    The response to the pandemic has shown the speed of mobilization and vaccine science at its best.

    Faced with an unprecedented challenge, governments, international organizations, the health care industry, and global health experts have come together on a scale never seen before. The result has been the development of multiple vaccines in record time and more than three billion doses administered worldwide.

    It’s a remarkable achievement, which shows what we are capable of when we act together and in the spirit of cooperation and solidarity.

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    But the coronavirus has also laid bare entrenched inequities that continue to perpetuate poor health and well-being in already vulnerable communities. Of those billion-plus vaccines, fewer than 2% have been dispensed in Africa.

    It is one of the key reasons the continent now finds itself gripped by a deadly third wave, which could claim more lives than the first two combined.

    The Tony Blair Institute for Global Change in its report entitled Africa’s Perfect Storm, set out the challenge and the threat if we do not take action: “The international community, both vaccine manufacturers and governments, need to increase support to African countries both in terms of vaccine supply and rollout by recognising that the battle against COVID-19 requires a global effort and that the increasing vaccine inequality we are witnessing today is a danger not only to Africa but for the global community.”

    Vaccines on the ground

    There is no lack of will from the global community. Billions of dollars have been pledged to the Gavi COVAX Advance Market Commitment, a global initiative to ensure vaccine supply reaches low- and middle-income countries. In addition, more and more countries are starting to donate from their own supply and direct them to where they are most needed.

    Developing, producing, and supplying a vaccine for the world is an extraordinarily complicated challenge and we have all learned many lessons.

    —

    For Africa, this is translating into vaccines on the ground and protecting the lives of millions of people. It is a remarkable display of global collaboration, which we in Africa are truly grateful for.

    But a looming challenge has been producing enough vaccines to meet the global demand. COVAX is expecting a strong increase in vaccine availability later this year as supplies from new manufacturers become available, but we are still falling short in our effort to bridge the vaccine equity gap.

    Given the scale and urgency of the challenge, we must go further. The World Health Organization has called for an “all-out, no regrets, accelerated building up of new vaccine manufacturing hubs.” WHO Director-General Tedros Adhanom Ghebreyesus has highlighted that for this to happen quicker, pharmaceutical companies must share their licenses, know-how, and technology.

    More than 355,000 doses of COVID-19 vaccines shipped by COVAX arrived in Niamey, Niger. Photo by: Dejongh / UN0440979 / UNICEF

    We agree with WHO that vaccine licensing is key to unlocking the supply challenge. While some have argued for a blanket waiver of intellectual property rights under the Agreement on Trade-Related Aspects of Intellectual Property Rights, or TRIPS, this is not a quick fix to immediately increase the supply of vaccines. In fact, this approach would take many more months to yield any extra doses, which is far too late for millions of people.

    The ‘third way’

    Instead, we are committed to a different approach, which the World Trade Organization’s Director-General Ngozi Okonjo-Iweala has called the “third-way.”

    COVAX marketplace to fill ‘short-term bottlenecks’ in vaccine production

    The marketplace initially will cater to 10-15 participants involving COVAX vaccine manufacturers and suppliers of key materials “most urgently needed.”

    For us, this involves a combination of not-for-profit pricing and technology transfers to boost production. Through this approach, we have already created more than a dozen new regional supply chains around the world to respond to community needs closer to where they are.

    This has allowed us to supply vaccines all over the world, contributing more than half a billion doses to the global fight against COVID-19. We were also the first vaccine manufacturer to commit to COVAX, supplying more than 90% of the vaccine to more than 127 participating countries, including 38 African countries at the end of June. Countries such as Ghana, Côte d'Ivoire, Kenya, Rwanda, and Ethiopia have all benefited from this approach.

    Developing, producing, and supplying a vaccine for the world is an extraordinarily complicated challenge and we have all learned many lessons on the way.

    These are lessons that should not merely be carried into future pandemic preparedness — they must be addressed right now. Entire communities and economies are depending on it.

    As things stand, just over 1% of people in Africa have been fully vaccinated. We still have a long way to go but we believe our approach can bring much-needed relief to the world’s most vulnerable communities.

    This will only be possible if we work together, apply our lessons learned, and do what is necessary to vaccinate the whole world, not just portions of it.

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    The views in this opinion piece do not necessarily reflect Devex's editorial views.

    About the author

    • Barbara Nel

      Barbara Nel

      Barbara Nel is country president for the African cluster at AstraZeneca, with responsibility for South Africa, sub-Sahara, and Francophone Africa. She has been with AstraZeneca since 2011, successfully managing and delivering business priorities in a number of roles in emerging markets globally and working collaboratively across multifunctional departments.

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