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    • Opinion
    • Opinion: Global health

    The global health landscape will never be the same — and it shouldn’t be

    Opinion: At this point, we cannot talk about small cosmetic changes needed in the global health system — we need a structural reform to make our multilateral system more efficient, robust, and fair.

    By Axel R. Pries // 06 October 2025

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    Recent global funding cuts must be a catalyst for Africa’s prosperity
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    How to make United Nations high-level meetings work for global health
    How to make United Nations high-level meetings work for global health

    Radical shifts in aid and development are forcing the entire global health sector to make long-overdue adjustments and to eliminate well-entrenched habits in addressing the challenging question: How do we design a new global health ecosystem that is effective, resilient, and fair?

    2025 is unfolding as a year of unprecedented disruption and political turmoil for the global health and international development sector, challenging paradigms developed over decades. This change has largely been triggered by the decision of the Trump administration to withdraw the United States from the World Health Organization, even though the U.S. helped establish it 77 years ago and was its largest donor.

    The U.S. administration has also made major funding cuts to development and humanitarian aid, leading to enormous hardship and increased mortality in many of the world’s most vulnerable communities.

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    Read more:

    ► Are aid cuts an opportunity to redesign health data systems?

    ► What’s broken in global health, and how do we fix it?

    ► Helen Clark: Global health reforms need ‘adult conversation’

    • Global Health
    • Democracy, Human Rights & Governance
    Printing articles to share with others is a breach of our terms and conditions and copyright policy. Please use the sharing options on the left side of the article. Devex Pro members may share up to 10 articles per month using the Pro share tool ( ).
    The views in this opinion piece do not necessarily reflect Devex's editorial views.

    About the author

    • Axel R. Pries

      Axel R. Pries

      Dr. Axel R. Pries has been president of the World Health Summit — the leading platform for global health — since 2021. A physician and physiologist by training, he previously served as dean of Charité – Universitätsmedizin Berlin. He also presided over the Biomedical Alliance in Europe and is pro-rector at Danube Private University in Krems, Austria.

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