The National Research Council (CNR) Institute for Genetic and Biomedical Research (IRGB) has the goal of understanding the causes and the mechanisms underlying diseases with a genetic component, both with simple or complex modes of inheritance.

The IRGB has a long-standing experience in elucidating genetic and epigenetic factors at the base of common diseases. The institute’s primary efforts are carried out through a number of projects performed by different groups operating in different sites in Sardinia (Monserrato, Lanusei, Sassari and Pula) and in Milan.

Among the projects being performed in Sardinia, five (the ProgeNIA/SardiNIA Study; the Autoimmunity Study; the Sardinian Genome Project, the Sardinian Transcriptome Project and the Immune Deployment Project), are highlighted here.