Kala-Azar Medical Research Centre
Prof. (Dr.) Shyam Sundar laid the foundation of Kala Azar Medical Research Centre ( KAMRC) as a unit of SITARAM MEMORIAL TRUST in the year 1994. Currently Dr. Shyam Sundar is professor at Banaras Hundu University , Varanasi U.P. KAMRC is being administered by Mr. Anil Sharma for last two decades with the passion to eliminate Kala Azar disease from the roots. Recognised by state and Central government of Republic of India, KAMRC is constantly striking hard to achieve its goal with the help of many untold but ruthless voluntarily efforts of numerous scientists, doctors, para-medical personnel and non-technical people from different corners of the society.
Majority of Kala Azar disease cases are found in the poorest-of-the poor sect of the society where the biggest challenge is to be aware about this disease and get cured for life. Marching together with Bihar Government initiative towards Kala Azar prevention and elimination they own the responsibility of making the people aware about this disease and searching the cases from far doors and farms so that they can be attended for the right treatment. They are happy and feel enthusiastic that for patients of Kala Azar there is no difference in treatment and post-treatment procedures from the primary health centres established by the state government.
They also leap ahead for the development and advancements of new medicines and procedures to cure and treat Kala Azar cases with many research scholars and sometimes with the dedicated units of the various medicine producing companies. They help them by observing all the procedures and protocols to conduct any case study for the advancements of Kala Azar medicines.
People across the globe help us or themselves to understand the origin of Kala Azar by using their incubator technology and centre facilities. At their incubation centre the kala Azar bees are incubated so that they offer open and equal opportunity to different scholars to understand the origin and find a state-of-art solution to kill it permanently from the globe.
Kala Azar as Visceral leishmaniasis (VL) is a disease caused by protozoan parasite of the genus Leishmania. This is a infectious disease which migrates to internal organs such as liver, spleen and bone marrow. If this disease is not treated till cure it may be fatal. Signs and symptoms include fever, weight loss, fatigue, anemia, and substantial swelling of the liver and spleen. According to the World Health Organization (WHO) this may be the emerging problem of HIV/VL co-infection.
When people develop visceral leishmaniasis (VL), the most typical symptoms are fever and the enlargement of the spleen, with enlargement of the liver sometimes being seen as well. The blackening of the skin that gave the disease its common name in India does not appear in most strains of the disease, and the other symptoms are very easy to mistake for those of malaria. Misdiagnosis is dangerous, as without proper treatment the mortality rate for kala-azar is close to be sure.
Even with recovery, kala-azar does not always leave its hosts unmarked. Some times after successful treatment—generally a few months with African kala-azar, or as much as several years with the Indian strain—a secondary form of the disease may set in, called post kala-azar dermal leishmaniasis, ( PKDL ). This condition manifests first as small, measle-like skin lesions on the face, which gradually increase in size and spread over the body. Eventually the lesions may coalesce to form disfiguring, swollen structures resembling leprosy, and occasionally causing blindness if they spread to the eyes. This disease is not the same as VL.
The insect vectors are species of sandfly. Sandflies are tiny flies, measuring 3–6 mm long by 1.5–3 mm in diameter, and are found in tropical or temperate regions throughout the world. The larvae grow in warm, moist organic matter (such as old trees, house walls, or waste) making them hard to eradicate.
The life cycle of Leishmania is completed in two hosts, humans and sandflies. The adult female sandfly is a bloodsucker, usually feeding at night on sleeping prey. When the fly bites an individual infected with Leishmania, the pathogen is ingested along with the prey's blood.
The gold standard for diagnosis is visualization of the amastigotes in splenic aspirate or bone marrow aspirate.
The K39 dipstick test is easy to perform, and village health workers can be easily trained to use it. The kit may be stored at ambient temperature and no additional equipment needs to be carried to remote areas.See more