Mainline is a non-governmental organisation based in Amsterdam , the Netherlands . Embracing a Harm Reduction approach, Mainline works to improve the health and quality of life of (injecting) drug users. Cooperating with governmental and non-governmental organizations in various regions of the world Mainline focuses on prevention of drug-related infectious diseases such as HIV and hepatitis B and C as well as care and support for those drug users already infected. Drug abstinence is not a prerequisite. Mainline's approach is pragmatic, holisitc and non-judgemental.

Mainline's mission is to promote health and fulfill the human rights of people who use drugs:

without a primary focus on the reduction of drug use and with respect for the individual drug user's freedom of choice and capabilities.

Vision
All of Mainline’s activities are carried out in the interests of harm reduction.

Harm reduction offers people the chance to control their use of drugs and take back their own lives within realistic boundaries.

Harm reduction thus restores human dignity and increases quality of life for people who use drugs.