The Ministry of Public Health (MSP) is the ministry of the Government of Uruguay responsible for establishing public health policies and strategies, in order to contribute to the improvement of the health of the inhabitants of the Nation.

The ministry's mission is to establish policies and strategies for the fulfillment of essential public health functions, as well as to guide the functioning of the National Integrated Health System (SNIS). The Ministry is headquartered in the 18 de Julio Avenue in Barrio Cordón, Montevideo. This government portfolio is in charge of the National Institute for Donation and Transplantation of Cells, Tissues and Organs. The current Minister of Public Health is Daniel Salinas, who has held the position since March 1, 2020.