NAFOPHANU is the national umbrella organization for People living with HIV (PLHIV) in Uganda established in May 2003 to coordinate networks of PLHIV. They are a national Non-Government Organization (NGO) whose mandate is; Advocacy, Resource mobilization, Partnerships building and Information sharing.

The PLHIV networks under NAFOPHANU are made up of community members who have organized themselves to access services and provide peer support to each other. A number of organized groups receive funding from NAFOPHANU using a sub-granting system for Advocacy, Income Generation, Sharing information and community engagement in HIV prevention and Psycho-social support. The organization and its partners have built the capacity of network members to be able to demand for and access information and services as well as leading responsible lives to avoid re/co-infection.