Coalition for Epidemic Preparedness Innovations (CEPI)
CEPI – the Coalition for Epidemic Preparedness Innovations – is a new international non-profit coalition aspiring to build a system that can tackle the barriers to develop vaccines against those epidemic infections for which the usual commercial incentives for development are inadequate. CEPI will advance safe, effective and affordable vaccines that can help to contain outbreaks at the earliest possible stage. CEPI was founded in August 2016 by the Government of Norway, the Bill & Melinda Gates Foundation, the Wellcome Trust, the World Economic Forum, and India’s Department of Biotechnology.
CEPI wants to stop future epidemics by developing new vaccines for a safer world.
Vaccines are one of the world’s most important health achievements. Yet their life-saving potential hasn’t yet been realised for many known and unknown epidemic threats, particularly in low-income countries, where the risks and needs are often greatest.
Vaccines contributing to preventing outbreaks of emerging infectious disease from becoming humanitarian crises.
CEPI will build a new system to advance the development of safe, effective and affordable vaccines, ensuring that price is not a barrier to access for populations most at need. This will offer the world an insurance policy against the growing threat from emerging infectious diseases. CEPI will be a partnership of public, private, philanthropic and civil organisations to stimulate, finance and co-ordinate vaccine development against priority threats, particularly when development is unlikely to occur through market incentives alone.
CEPI will pursue a proactive (“just-in-case”) and accelerated (“just-in-time”) vaccine development strategy for epidemic threats by:
- Moving vaccine candidates through late preclinical studies to proof of concept and safety in humans before epidemics begin, so that larger effectiveness trials can begin swiftly in an outbreak and small stockpiles are ready for potential emergency use;
- Building technical platforms and institutional capacities that can be rapidly deployed against new and unknown pathogens.
New vaccines could prevent deadly infectious diseases that have epidemic potential from becoming global health emergencies.
Vaccine development needs to start long before an epidemic so that final clinical trials or emergency deployment can begin swiftly in an outbreak. But the vaccines we need aren’t being developed often enough or quickly enough.
Making vaccines that work and are safe isn’t easy – it typically takes more than 10 years -- but we know it can be done. The risks and costs are especially significant for epidemic diseases. Outbreaks come and go, and recent events have shown us that they hit poor countries the hardest, putting immense pressure on already fragile health systems.
Once a vaccine is created, trials are harder to conduct than for more commercially viable vaccines, and complex regulations and laws that vary from country to country can delay getting vaccines to the people who desperately need them.
CEPI – the Coalition for Epidemic Preparedness Innovations – will overcome these barriers with a new model for funding vaccine developments against epidemic diseases. This will contribute to the health security the world needs.
CEPI is in start-up phase until the end of 2017. During this period, an Interim Secretariat provided by the Government of Norway is coordinating CEPI activity with close support from the Government of India, Wellcome Trust, the Bill & Melinda Gates Foundation, and the World Economic Forum.
CEPI is actively seeking partnerships with governments, potential funders, industry partners, regulators, and civil society organisations with an interest in building a proactive and accelerated approach to vaccine development and delivery
Vaccines are part of a global solution
CEPI (pronounced 'seppy') is a new alliance between governments, industry, academia, philanthropy, intergovernmental institutions, such as the World Health Organization, and civil society.
They exist to finance and coordinate the development of new vaccines to prevent and contain infectious disease epidemics. As epidemics disproportionately affect low-income countries, CEPI will ensure that the vaccines they help to develop are affordable, so that price is never a barrier to access, and they are available to populations with the most need.
They will thus ensure that vaccines play the fullest possible part in containing infections with epidemic potential, to prevent them becoming public health emergencies, and build a safer world.See more