The M-Coalition is the only regional HIV/AIDS advocacy network specifically devoted to the needs of LGBT in the MENA region. It was established in January 2014 in response to a shared concern that current HIV strategies and responses in the region are not adequately responsive to MSM and later expanded to include all aspects of health for MSM. In 2018, M-Coalition officially started working on health needs for Lesbian women and transgender populations. The M-Coalition is governed by a collegially appointed, 7-member steering committee of regionally recognized LGBT advocates and HIV/AIDS professionals drawn from multiple countries in the MENA region.
The M-Coalition works through advocacy, information exchange, knowledge production, networking, and capacity building activities, sustained over time at the local and regional level. The M-Coalition also strives to involve members of the LGBT community and people living with HIV at all levels of its strategy, policy development and implementation, and internal governing processes.